Endocrine Abstracts

Introduction: Autoimmune adrenal injury is the most common cause of primary adrenal failure (PAF) (70–90%). Antiphospholipid syndrome (APS) that characterized by thrombosis and abortus may be a reason of PAF. In this presentation we reported a case of primary adrenal failure due to primary antiphospholipid syndrome.Case: A 34-year-old boy was brought to emergency service due to loss of consciousness. In physical examination patients was confused, bl...

Introduction: Oncocytic (Hurthle cell) carcinoma is consisted of <5% of thyroid cancer but most metastasizing cancer type among differentiated thyroid cancer. We presented an oncocytic carcinoma with sternum metastasis.Case: A 68-year-old women admitted to endocrinology policlinic with complaint of a mass in her neck. She was diagnosed hyperthyroidism and she was using thionamid for 6 months. Her medical history revealed hypertension for 3 years and ...

Aim: Thyroid tissue originates from foramen cecum located in the base of the tongue and with embryonal development it descends through thyroglossal duct to its normal location. A total or partial failure in thyroid tissue descending causes ectopic thyroid tissue. One of this ectopic region is lingual region. We presented two case of ectopic thyroid tissue.Case 1: A 18-year-old female that uses levothyroxine 100 mcg/day for hypothyroidism admitted to endo...

Aim: Diabetes mellitus affects many systems and one of them is skin. Skin findings among diabetic patients reported 30–71%. Skin findings may be due to direct metabolic effects of diabetes but complications and drugs may be cause as well. In this study our aim was to investigate the skin findings and prevalence among diabetic patients that admitted to endocrinology policlinic.Method: 81 patients involved to study, skin examination of the patients we...

Background: X and Y chromosomes carry many genes that direct development and gametogenesis. Rearrangements associated with X chromosome may have a role in abnormal phenotypes. We presented a case of primary amenorrhea with normal karyotype but centromere thickness in 13th chromosome (13 cenh+), this is the first case in literature.Case: A 18-year-old woman admitted to endocrinology clinic with complaints of primary amenorrhea and a failure in ...

Background: PCOS is one of the most common disorders affecting at least 5–10% of women of reproductive age. Increased prevalance of autoimmune thyroiditis and goiter were reported in PCOS patients. This study investigated the prevalance of hypothyroidism, thyroid autoimmunity, ultrasonographic features and presence of nodules in PCOS patients and compare them with the control group. We also aimed to detect correlation of thyroid volume (TV) with serum IGF1 levels in patie...

Introduction: Wolfram syndrome has characterized by central diabetes insipidus (DI), diabetes mellitus (DM), optic atrophy (OA) and deafness. In this report we presented a Wolfram syndrome with hypergonadotropic hypogonadism.Case: A 18-year-old girl who has diabetes for 6 years was hospitalized due to blood sugar irregularity. Her medical history revealed frequent urination and enuresis for 2–3 years and primary amenorrhea. Furthermore she had hear ...

Aim: Our aim was to investigate the frequency of isolated maternal hypothyroxinemia (IMH) at gestational diabetes mellitus (GDM)Material and method: Fifty women with GDM aged between 20–41 and 100 healthy pregnant aged between 17–41 were involved to study. Patients that have thyroid disease and low free T4 levels at first trimester were ruled out. Thyroid function tests of patients and healthy controls were assessed at first, second ...

Background: Endocrine-related adverse effects of immune check-point inhibitors (ICIs) have been identified in growing number of cancer patients.Case presentation: A 49-year-old male with laryngeal cancer applied to ouroutpatient clinic with weakness, loss of appetite, weight loss, nausea and vomiting for the last three weeks. He was diagnosed with T3N1M0 laryngeal squamous cell cancer seven months before this admission and was given concurrent cisplatin ...

Introduction: Pregnancy occurs relatively rare women with acromegaly. However, in recent years, pregnancy has become more likely to occur in acromegalic women possibly due to improvements in acromegaly treatment, and advanced assisted reproduction techniques.Methods: In this case series, we retrospectively analyzed 11 pregnancies of 8 acromegalic women followed in the university hospital in a time range between 2009–2019. Data were obtained from pa...